Ideas: More AI-resilient biosecurity with the Paraphrase Project

Microsoft’s Eric Horvitz and guests Bruce Wittmann, Tessa Alexanian, and James Diggans discuss the Paraphrase Project—a red-teaming effort that exposed and secured a biosecurity vulnerability in AI-driven protein design. The work offers a model for addressing AI’s dual-use risks. The post Ideas: More AI-resilient biosecurity with the Paraphrase Project appeared first on Microsoft Research.

2025/10/6
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When AI Meets Biology: Promise, Risk, and Responsibility

Microsoft researchers reveal a confidential research effort that explored how open-source AI tools could be used to bypass biosecurity checks—and helped create fixes now influencing global standards. The post When AI Meets Biology: Promise, Risk, and Responsibility appeared first on Microsoft Research.

2025/10/6
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Using AI to assist in rare disease diagnosis

New research from Microsoft, Drexel, and the Broad explores how generative AI could support genetic professionals in rare disease diagnosis. The post Using AI to assist in rare disease diagnosis appeared first on Microsoft Research.

2025/9/22
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Tool-space interference in the MCP era: Designing for agent compatibility at scale

As agentic AI ushers in a new era marked by tool expansion, systems are converging, and complexity is rising. Microsoft Research explores the Model Context Protocol (MCP) as a new standard for agent collaboration across fragmented tool ecosystems. The post Tool-space interference in the MCP era: Designing for agent compatibility at scale appeared first on Microsoft Research.

2025/9/12
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RenderFormer: How neural networks are reshaping 3D rendering

RenderFormer, from Microsoft Research, is the first model to show that a neural network can learn a complete graphics rendering pipeline. It’s designed to support full-featured 3D rendering using only machine learning—no traditional graphics computation required. The post RenderFormer: How neural networks are reshaping 3D rendering appeared first on Microsoft Research.

2025/9/11
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Breaking the networking wall in AI infrastructure 

Datacenter memory and network limits are restraining AI system performance. MOSAIC uses microLEDs and a wide-and-slow optical architecture to deliver faster, longer, more reliable, and energy efficient connections that could transform AI cluster designs. The post Breaking the networking wall in AI infrastructure  appeared first on Microsoft Research.

2025/9/9
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Crescent library brings privacy to digital identity systems

Crescent helps make digital IDs private by preventing tracking across uses while letting users only disclose what’s necessary from their credentials. The post Crescent library brings privacy to digital identity systems appeared first on Microsoft Research.

2025/8/27
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Applicability vs. job displacement: further notes on our recent research on AI and occupations

Recently, we released a paper Working with AI: Measuring the Occupational Implications of Generative AI that studied what occupations might find AI chatbots useful, and to what degree. The paper sparked significant discussion, which is no surprise since people care deeply about the future of AI and jobs--that’s part of why we think it’s important to study these topics. The post Applicability vs. job displacement: further notes on our recent research on AI and occupations appeared first on Microsoft Research.

2025/8/22
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Coauthor roundtable: Reflecting on healthcare economics, biomedical research, and medical education

For the series finale, Peter Lee, Carey Goldberg, and Dr. Zak Kohane compare their predictions to insights from the series’ most recent guests, including experts on AI’s economic and societal impact, leaders in AI-driven medicine, and doctors in training. The post Coauthor roundtable: Reflecting on healthcare economics, biomedical research, and medical education appeared first on Microsoft Research.

2025/8/22
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MindJourney enables AI to explore simulated 3D worlds to improve spatial interpretation

MindJourney can enable AI to navigate and interpret 3D environments from limited visual input, potentially improving performance in navigation, planning, and safety-critical tasks. The post MindJourney enables AI to explore simulated 3D worlds to improve spatial interpretation appeared first on Microsoft Research.

2025/8/21
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